ZIA CP004410-08165 (ZIA) | |||
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Title | Family Studies | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | A Tucker, Margaret | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $419,608 | Project Dates | 01/01/2002 - N/A |
Fiscal Year | 2009 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Colon/Rectum (20.0%) Kidney Cancer (20.0%) Kidney Disease (20.0%) Leukemia (20.0%) Melanoma (10.0%) Uterine (10.0%) |
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Research Type | |||
Normal Functioning Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
We are focusing on the clinical, epidemiologic, genetic, and laboratory investigations of individuals affected with genodermatoses with an increased risk of internal malignancy or skin cancer. Our aim is to elucidate the mechanisms that contribute to benign and malignant diseases. We recruit and examine individuals and collect samples obtained from affected individuals and their relatives for cytogenetic, haplotype, sequencing and other molecular methods. The genomic localization of single and complex gene traits that predispose to genodermatoses and skin cancer is determined using various analytic and statistical genetic methods. |