ZIA CP010198-03036 (Z1A) | |||
---|---|---|---|
Title | CONCERN Study (Colorectal Neoplasia Screening with Coloscopy in Average-risk Wome | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Sinha, Rashmi | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $5,628 | Project Dates | 00/00/0000 - 00/00/0000 |
Fiscal Year | 2016 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Alcoholism Research (20.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) Chemoprevention (5.0%) |
Colon/Rectum (100.0%) | ||
Research Type | |||
Cancer-Related Biology
Dietary Interventions to Reduce Cancer Risk and Nutritional Science in Cancer Prevention |
|||
Abstract | |||
The primary purpose of the study is to determine the extent to which advanced neoplastic lesions will be missed if clinicians only perform sigmoidoscopies rather than full colonoscopies as a screening procedure and to resolve current debate about the significance of sigmoidoscopic detection of single, small, tubular ademonas (i.e., do they imply greater risk for large adenomatous polyps or colorectal cancer at other sites beyond the reach of the sigmoidoscope, or is there no increaded risk?). Women enrolled in the trial receive colonoscopy during which all identified polyps are removed and also during which pinch biopsies of apparently-normal tissue are taken. In addition, before the colonoscopy is performed, patients will have blood drawn and answer a brief questionnaire on risk factors for colorectal cancer." |