ZIA CP010196-03152 (Z1A) | |||
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Title | AARP prospective study of diet and cancer | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Sinha, Rashmi | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $1,229,987 | Project Dates | 00/00/0000 - 00/00/0000 |
Fiscal Year | 2016 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Aging (50.0%) Alcoholism Research (20.0%) Basic Behavioral and Social Science (20.0%) Behavioral and Social Science (20.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) Digestive Diseases (5.0%) |
Bladder (5.0%) Brain (5.0%) Breast (5.0%) Colon/Rectum (10.0%) Esophagus (5.0%) Kidney Cancer (5.0%) Kidney Disease (5.0%) Larynx (5.0%) Leukemia (5.0%) Liver Cancer (5.0%) Lung (5.0%) Multiple Myeloma (5.0%) Ovarian Cancer (5.0%) Pancreas (5.0%) Pharynx (5.0%) Prostate (5.0%) Stomach (5.0%) Thyroid (5.0%) Uterine (5.0%) |
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Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Dietary Interventions to Reduce Cancer Risk and Nutritional Science in Cancer Prevention |
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Abstract | |||
This is a prospective cohort study of diet and cancer in relation to several major cancers, especially breast, prostate, and colorectal malignancies. The cohort comprises 50-69 year-old male and female members of the American Association of Retired Persons (AARP). in 1995-6 we mailed baseline questionnaires to 3.5 million AARP members. Over 615,000 AARP members responded, with over 540,000 providing adequate dietary data. Preliminary analysis indicates that the cohort, both men and women, has the desired wide distributions of percent calories from fat, dietary fiber, fruits and vegetables, and red meat. Approximately 330,000 of the initial respondents (with satisfactory data) returned a second questionnaire containing questions on expsures not assessed in the first instrument. An end point ascertainment pilot study determined that cohort incidence rates for major cancers, determined from registry data, are consistent with SEER rates. Moreover, loss to follow-up would be small, causing neglibible bias in relatvie risk estimates." |