ZIA CP010123 02342 (ZIA) | |||
---|---|---|---|
Title | Shanghai prospective cohort study of occupational exposures and cancer risk among | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Rothman, Nat | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $65,323 | Project Dates | null - null |
Fiscal Year | 2018 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Alcoholism Research (3.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) Digestive Diseases (40.0%) Pesticides (10.0%) Sleep Disorders (30.0%) |
Breast (10.0%) Colon/Rectum (20.0%) Lung (10.0%) Stomach (55.0%) Thyroid (5.0%) |
||
Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Interactions of Genes and/or Genetic Polymorphisms with Exogenous and/or Endogenous Factors |
|||
Abstract | |||
This prospective cohort study will evaluate occupational and environmental risk factors for cancer among women in Shanghai, China. The interview will elicit information on demographic background, diet, lifestyle factors, medical history, lifetime occupational history and residential history for the past 25 years. In addition, the women will be asked for information on their husbands' current and usual occupations, and demographic and a few other exposure factors. A spot urine sample and 10 ml of blood will be collected from all cohort members. Among participants who did not provide a blood sample, a buccal cell sample will be collected. Cohort members and their husbands will be followed for cancer outcomes through annual recontact and linkage with files of the population-based Shanghai Cancer Registry, of the Shanghai Vital Statistics, and of the Shanghai Resident Registry. Medical records and pathology slides will be reviewed for all cancer cases to verify their diagnosis. Post-diagnostic blood samples will be obtained from all cohort members diagnosed with cancer during the follow-up period and stored for future methodologic and etiologic studies. |