ZIA BC 011550 (ZIA) | |||
---|---|---|---|
Title | Anakinra for neutrophilic pustular skin disease | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Cowen, Edward | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $151,876 | Project Dates | 00/00/0000 - 00/00/0000 |
Fiscal Year | 2017 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Autoimmune Diseases (90.0%) Cancer (100.0%) |
N/A | ||
Research Type | |||
Systemic Therapies - Clinical Applications | |||
Abstract | |||
To date, 16 patients have enrolled on this treatment protocol. A goal of 25-30 patients has been established to determine if anakinra has efficacy for pustular neutrophilic skin disease. In addition to the clinical outcomes, tissue and serum samples are being sent to the lab of Raphaela Goldbach-Mansky, Maria Morasso, Alison McBride, and Nehal Mehta in order to further investigate the biologic pathways responsible for pustular psoriasis, including risk of cardiovascular disease as assessed by PET/CT. |