ZIA CP010133-10716 (ZIA) | |||
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Title | NASA project on risk of heart disease from space radiation | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Little, Mark | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $16,613 | Project Dates | 00/00/0000 - 00/00/0000 |
Fiscal Year | 2017 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Aging (10.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Brain (10.0%) Heart (90.0%) |
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Research Type | |||
Development and Characterization of Model Systems
Application of Model Systems |
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Abstract | |||
"""This is a new NASA funded (NSBRI) project with PI Dr John Baker (Medical College of Wisconsin) that I am a consultant on. Funding requested is to cover travel costs. The proposed studies center on an assessment of the degenerative tissue effects of space radiation on cardiac risk factors and cardiac function. Our central hypothesis is that whole body exposure to space-relevant doses of solar particle event (SPE) protons and galactic cosmic rays (GCRs) will increase the risk for developing degenerative cardiovascular disease. Two Specific Aims are proposed to directly address the issue of cardiovascular risk using experimental approaches in a rat model and mathematical modeling of rat and human data relevant to the research questions. The proposed investigations directly address important aspects of the NASA Human Research Program (HRP) Degenerative Tissue Gaps, as set forth in the Human Research Roadmap. HRP gaps are identified that are addressed by each Specific Aim. The proposed research will provide important information to help close these gaps. Renamed from """"Determination of risk for and occurrence of heart disease from space radiation"""" to """"NASA project on risk of heart disease from space radiation""""""" |