ZIA CP010168 - 10039 (ZIA) | |||
---|---|---|---|
Title | Maternal and Umbilical Cord Hormone Concentrations in Monochorionic and Dichorion | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Troisi, Rebecca | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $13,117 | Project Dates | 01/01/2004 - 00/00/0000 |
Fiscal Year | 2015 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Breast (80.0%) Prostate (10.0%) Testes (10.0%) |
||
Research Type | |||
Cancer-Related Biology
Endogenous Factors in the Origin and Cause of Cancer |
|||
Abstract | |||
The proposed study involved collecting maternal and cord blood samples from monochorionic twin, dichorionic twin, and singleton pregnancies of similar gestational age to quantify differences in concentrations of several hormones and other pregnancy products including estriol, estradiol, estrone, testosterone, androstenedione, dehydroepiandrosterone (DHEA), DHEA-sulfate, progesterone, AFP, prolactin, IGF and IGF-binding protein 3. Data from medical records and pathology reports were abstracted to provide information on the mother, baby, pregnancy, and placenta. The work was done at Dartmouth Hitchcock Medical Center, Dartmouth Medical School. Blood samples labeled with a unique ID number were sent to Bioreliance, NCI's contractor only, for preperation and shipment to the laboratory that would perform the hormone assays. NCI received the abstracted data in electronic form. No personal identifying information was received by NCI or its contractor. The study was approved by Dartmouth Medical School. Pregnancy hormones were measured and are currently being analyzed. |