ZIC BC 011198 (ZIC) | |||
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Title | Generation of mouse model of human cancer | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Tessarollo, Lino | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $214,265 | Project Dates | 10/01/2009 - N/A |
Fiscal Year | 2009 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Cancer (100.0%) Digestive Diseases (33.0%) |
Brain (34.0%) Colon/Rectum (17.0%) Kidney Cancer (33.0%) Kidney Disease (33.0%) Liver Cancer (16.0%) Nervous System (34.0%) Urinary System (33.0%) |
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Research Type | |||
Normal Functioning Cancer Initiation: Oncogenes and Tumor Suppressor Genes |
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Abstract | |||
We keep providing CCR investigators with the most recent and advanced technological knowledge on how to manipulate the mouse genome to best mimic human disease. This is a very difficult task because every year we learn more about the genetic component of disease in human and about the differences between the human and mouse. At the same time we are constantly improving our tools to facilitate the targeting of the mouse genome and we ensure that our methods are versatile and are economically sound. |