Z01 BC 010687 (Z01) | |||
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Title | Histology Core Laboratory | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Kleiner, David | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $734,825 | Project Dates | 10/01/2004 - N/A |
Fiscal Year | 2008 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Autoimmune Diseases (3.0%) Bone Marrow Transplantation (10.0%) Cancer (100.0%) Digestive Diseases (10.0%) Inflammatory Bowel Disease (5.0%) Metastasis (30.0%) |
Cervical Cancer (2.0%) Colon/Rectum (5.0%) Kidney Cancer (5.0%) Kidney Disease (5.0%) Liver Cancer (10.0%) Lymphoma (5.0%) Melanoma (10.0%) Non Hodgkins Lymphoma (5.0%) Ovarian Cancer (2.0%) Prostate (10.0%) Sarcoma (2.0%) Sarcoma, Bone (Sarcoma Subset) (1.0%) Sarcoma, Soft (Sarcoma Subset) (1.0%) Skin (10.0%) |
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Research Type | |||
Resources and Infrastructure Related to Detection, Diagnosis, or Prognosis Resources and Infrastructure Related to Treatment and the prevention of recurrence |
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Abstract | |||
The Histology Laboratory of the Laboratory of Pathology (LOP) is a core facility devoted to supporting the clinical activities of LOP. This consists of accessioning human tissues removed at surgery or in clinics, processing the tissues, preparing and staining slides for microscopy. It also processes slides and blocks submitted from laboratories outside the NIH on NIH patients or non-NIH patients. Within the LOP, the Histology lab serves the Surgical Pathology, Hematopathology, Postmortem Pathology, Cytopathology, and Ultrastructural and Pediatric Pathology sections as well as the Specialized Diagnostics Unit. During FY07, about 15,000 tissue blocks were prepared from over 6,300 specimens and over 100,000 slides were cut and stained. Additionally, the laboratory processes case material sent in consultation or for review prior to protocol entry for patients in the Clinical Center. This fiscal year over 60,000 consult slides on over 5800 cases were received. Although about 95% of effort is devoted to clinical duties, the Histology Laboratory also performs recuts of tissue blocks and does some routine staining for research projects in NCI by arrangement. This activity is coordinated with the tissue research request function of Clinical Operations. |