ZIABC010592 (ZIA) | |||
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Title | Comparative Genomic Hybridization of Neuroblastoma | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Khan, Javed | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $57,475 | Project Dates | 10/01/2003 - N/A |
Fiscal Year | 2012 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Cancer (100.0%) |
Brain (10.0%) Nervous System (80.0%) Neuroblastoma (70.0%) Sarcoma (20.0%) |
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Research Type | |||
Technology Development and/or Marker Discovery Resources and Infrastructure Related to Detection, Diagnosis, or Prognosis |
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Abstract | |||
Recurrent non-random genomic alterations are the hallmarks of cancer and the characterization of these imbalances is critical to our understanding of tumorigenesis and cancer progression. We are performing microarray based-comparative genomic hybridization (CGH) on SNP and other oligonucleotide microarrays in neuroblastoma. We have recently began using next generation sequencing techniques to detect all of the structural alterations found in neuroblasotmas including small and large insertions and deletions as well as translocations. |