ZIA CP010176-10291 (ZIA) | |||
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Title | Transplant cancer match | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Engels, Eric | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $23,528 | Project Dates | 07/21/2004 - N/A |
Fiscal Year | 2012 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) Organ Transplantation Research (60.0%) |
Hodgkins disease (10.0%) Kaposi Sarcoma (20.0%) Liver Cancer (10.0%) Multiple Myeloma (10.0%) Non Hodgkins Lymphoma (50.0%) |
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Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
Recipients of solid organ transplants are immunosuppressed due to receipt of medications to prevent rejection of the donor organ. This project evaluates cancer risk among solid organ transplant recipients. Goals of the project include: 1) description of the spectrum of cancer risk in solid organ transplant recipients; 2) elucidation of the role of oncogenic viruses in causing cancer in this setting; and 3) understanding the role of other factors in causing cancer, such as demographic factors, mismatch between donor and recipient, and specific immunosuppressive medication. This project also evaluates cancer risk among end-stage renal disease patients on long term dialysis. The project makes use of large registry databases, including the U.S. Scientific Registry for Transplant Research. Other studies may involve collection of medical history data or evaluation of biological specimens. Duplicate of 10362 |