ZIA SC 009392 (ZIA) | |||
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Title | Proteomic Analysis of Renal Tumors | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Merino, Maria | NCI Program Director | N/A |
Cancer Activity | N/A | Division | CCR |
Funded Amount | $191,665 | Project Dates | 10/01/1994 - N/A |
Fiscal Year | 2009 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Cancer (100.0%) |
Kidney Cancer (100.0%) Kidney Disease (100.0%) Urinary System (100.0%) |
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Research Type | |||
Technology Development and/or Marker Discovery Resources and Infrastructure Related to Detection, Diagnosis, or Prognosis |
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Abstract | |||
We will study the differences in cellular protein expression between normal and tumoral kidney tissues as well as the profile of protein expression in different tumor types of renal neplasms, using proteomics technology. The continuation of this line of work will hopefully lead to the discovery of new molecular markers important in the diagnosis and treatment of renal cancer. We will develop techniques that assist in the identification of proteins in paraffin-fixed tissues. Comparison analyses will be performed using frozen tissues. |