ZIA CP010126-10598 (ZIA) | |||
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Title | Ghana Breast Cancer | ||
Institution | NCI, Bethesda, Ma | ||
Principal Investigator | Brinton, Louise | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $24,862 | Project Dates | 04/05/2011 - N/A |
Fiscal Year | 2011 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Basic Behavioral and Social Science (50.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Breast (100.0%) | ||
Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
Background: There currently exists scant information on breast cancer that occurs among African women, although data suggest that, like African-American women, the cancers that develop among African women tend to occur at younger ages and have worse prognostic features than those occurring among American Caucasians. Given that breast cancer incidence rates are increasing in many African nations and that treatment options are limited, there is a critical need for better understanding the pathogenesis and identifying risk factors that might be used in primary prevention. Objectives: As an initial step in conducting a full-scale molecular epidemiologic study of breast cancer in Ghana, a pilot study will be conducted to determine the feasibility of all phases of the study. The pilot will test the infrastructure needed to conduct a molecular epidemiologic study, determine the number of available cases, define methods for subject recruitment (for both cases and comparison subjects), and assess procedures for collecting questionnaire based interviews, and processing, storing and transporting biologic specimens. Eligibility: Women of all ages who are diagnosed and treated for incident breast cancer at Korle Bu Hospital in Accra, Ghana. Design: Prospective case-control study. |