Title |
The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
|
Institution |
COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY
|
Principal Investigator |
WANG, TIMOTHY
|
NCI Program Director |
Daschner
|
Cancer Activity |
Cancer Etiology
|
Division |
DCB
|
Funded Amount |
$912,000
|
Project Dates |
12/07/2016 - 11/30/2023
|
Fiscal Year |
2018
|
Project Type |
Grant
|
Research Topics w/ Percent Relevance |
Cancer Types w/ Percent Relevance |
Cancer (100.0%)
Chemotherapy (100.0%)
Digestive Diseases (100.0%)
|
Colon/Rectum (25.0%)
Esophagus (25.0%)
Pancreas (25.0%)
Stomach (25.0%)
|
Research Type |
Endogenous Factors in the Origin and Cause of Cancer
Systemic Therapies - Discovery and Development
|
Abstract |
Summary/Abstract This project seeks to investigate the role of nerves and other stromal cells in the development of digestive cancers, including stomach, esophageal, colon and pancreas. The project builds on previous work that suggests that these elements can regulate stem cells,a nd that inhibiting stromal cells in the microenvironment, it may be possible to inhibit the development of tumors." |