Z01 CP010182-01030 (Z01) | |||
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Title | BCDDF: Breast cancer detection demonstration project followup study - I | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Gail, Mitchell | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $439,832 | Project Dates | 01/01/1979 - N/A |
Fiscal Year | 2008 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Breast Cancer (30.0%) Colon/Rectum (20.0%) Ovarian Cancer (20.0%) Uterine (10.0%) |
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Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
This follows about 60,000 women who were former participants in the joint NCI and ACS Breast Cancer Detection Demonstration Project (BCDDP), a nationwide breast cancer screening program conducted during the 1970s. The follow-up started in 1980, with ascertainment of cancer and mortality continuing through 1998. The BCDDP Follow-up Study is particularly valuable for ascertaining the risks and benefits of menopausal hormone replacement therapy associated with cancers of the breast and colon. Analyses are currently under way to examine the relationships between hormone replacement therapy and benign breast disease and to evaluate survival after breast cancer in relation to use of replacement hormones. Research efforts also have focused on mammographic parenchymal patterns and densities in relation to subsequent breast cancer risk and the relation of physical activity, adult diet, alcohol consumption at various ages, and use of certain medications to breast cancer risk. |