Z01 CP010190 (Z01) | |||
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Title | Genetic Epidemiology of Telomere Maintenance and Cancer Etiology | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Savage | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $722,145 | Project Dates | 01/01/2004 - N/A |
Fiscal Year | 2007 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Aging (14.915%) Hematology (36.281%) |
Colon/Rectum (3.628%) Leukemia (16.92%) Pharynx (16.326%) Prostate (29.088%) |
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Research Type | |||
Endogenous Factors in the Origin and Cause of Cancer | |||
Abstract | |||
Telomeres consist of long TTAGGG nucleotide repeats and associated proteins at the ends of chromosomes that are essential for the maintenance of chromosomal integrity. In order to preserve the chromosome end, the telomerase reverse transcriptase (TERT), |