ZIA CP010131 10745 (ZIA) | |||
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Title | Proton vs Photon - Randomized trial in breast cancer | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Berrington, Amy | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $65,394 | Project Dates | null - null |
Fiscal Year | 2018 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) |
Breast (100.0%) | ||
Research Type | |||
Resources & Infrastructure Related to Biology Exogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
The RADCOMP Trial is a 5-year randomized clinical trial for breast cancer that is evaluating the effectiveness of proton vs. photon therapy to reduce major cardiovascular events, reduce the incidence of recurrent and/or contralateral breast cancer, improve overall survival and compare the risk of second malignancies. REB investigators have been working with the extramural trial investigators to design methods to prospectively follow-up of the trial participants to determine the risks for cardiovascular effects and second cancers. This randomized clinical trial is the first of its kind to evaluate the effectiveness of proton therapy for breast cancer. |